Vaginal dryness: oestradiol eggs to treat it

Vaginal dryness and its annoying symptoms are very common in women who are women, but can also occur at other times in life, such as during pregnancy. A study published in May demonstrates that estradiol-based hormone replacement therapy would relieve vulvovaginal problems.

Painful sexual intercourse, urinary leakage ... Vaginal dryness results from the imbalance of the vaginal flora and manifests itself in the form of burns, irritations and itching. It occurs in up to 75% of postmenopausal women and is, in this case, due to hormonal deficiency, but can also happen to younger or at other periods of life. This results in a reduction of physiological vaginal secretions and lubrication during sexual intercourse, causing discomfort and even pain in nearly half of the patients concerned.

Several factors may explain the vaginal dryness such as unsuitable clothes, the depilation of the jersey, excessive hygiene, certain medications, the imbalance of the vaginal flora ... But the main cause remains the insufficient rate of hormones, which often occurs after 40 years.

Estradiol-based hormone replacement therapy

A study published in May online in Menopausse, the Journal of the North American Menopause Society (NAMS), reveals that estradiol-based hormone replacement therapy (HRT) would relieve vulvovaginal problems and provide comfort and improved overall quality of life for women with vaginal dryness. These eggs, tested in a double-blind controlled trial, would be much more effective than conventional vaginal lubricants, say the researchers.

Estradiol is the main active sex hormone of the three natural estrogens. Secreted by the ovaries, it plays a key role in the distribution of adipose tissue (the senses, hips, thighs), the development of external and internal genitalia, breast development, endometrial development and libido. . At menopause, the estradiol level falls between 0.04 and 0.18 nmol, causing vaginal dryness.

The NAMS study of 300 postmenopausal women demonstrates that low doses of estradiol administered by vaginal eggs greatly improves this problem by providing comfort, better quality of life and mood compared to double placebo. In contrast, treatment with vaginal moisturizers was found to be as ineffective as placebo.

"An improvement in the quality of life and sexual function"

"Although vaginal lubricants and moisturizers can help with vaginal dryness, they may not be effective for women with more severe vaginal changes because of the loss of hormones at menopause," says Dr. JoAnn Pinkerton , Executive Director of NAMS.

"Vaginal therapies, including low-dose vaginal estrogens and intravaginal dehydroepiandrosterone, relieve both vaginal dryness and painful intercourse.This study also showed an improvement in the quality of life and sexual function of the tablets. vaginal oestradiol versus a vaginal moisturizer Women with vaginal dryness and / or having painful intercourse should talk to their health care providers about the best option for their particular situation. "

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