Adenoma of the Prostate: Certain Drugs Increase the Risk of Type 2 Diabetes

Doctors do not recommend stopping treatment, but increasing patient monitoring.

Many medications have side effects but some may be more disturbing than others. Scottish and British researchers show that treatment against prostate adenoma increases the risk of type 2 diabetes. In their results, published in the British Medical Journalthey do not call for patients to change treatment but doctors to strengthen their supervision.

Drugs used to reduce the size of the prostate

Prostate adenoma, or benign hypertrophy, refers to a condition that primarily affects men over 50 years of age. With age, the size of their prostate increases and compresses the urethra. Ultimately, this causes discomfort when urinating, the main symptom of the disease.

Many men get 5-alpha reductase inhibitors: these drugs help to reduce the volume of the prostate. One of the known side effects is the appearance of erectile dysfunction. Previous studies have shown that they can also decrease the body's response to insulin, which is one of the symptoms of type 2 diabetes.

About 30% more risk

In this research, the researchers analyzed health data from approximately 55,000 men, taking 5-alpla reductase inhibitors, in the UK over an 11-year period. According to their findings, taking these drugs increases the risk of type 2 diabetes by a third. "These results should not be a cause for concern for men taking 5-alpha-reductase inhibitors", reassures Laurence Stewart, one of the authors of the study. On the contrary, it is according to him to the carers and doctors to redouble vigilance when they prescribe them and after, during the follow-up of their patients.

80% of men over age 80 have benign prostatic hypertrophy. Two million men in France would have some symptoms.

Video: Mayo Clinic Minute: Steam treatment for enlarged prostate (November 2019).